A Correlational Analysis of Academic Stress in Adolescents in Respect of Socio-economic Status

For students, the adolescent is a major transition in their lives since they make various decisions regarding all aspects of their lives such as academics, social life, and leisure activities. They have to struggle to meet the expectations of their parents which include desires related to their academic performance. In addition, society believes that studies with a high-rank from the reputed institute are a “passport” to a good job, high salaries, and high social status which is expected from students. As a result, the students are indirectly subjected to a variety of stressors mainly linked to academic success

Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection

Enteropathogenic and enterohemorrhagic bacterial infections in humans are a severe cause of morbidity and mortality. Although NOD-like receptors (NLRs) NOD2 and NLRP3 have important roles in the generation of protective immune responses to enteric pathogens, whether there is crosstalk among NLRs to regulate immune signaling is not known. Here, we show that mice and macrophages deficient in NOD2, or the downstream adaptor RIP2, have enhanced NLRP3-and caspases-11-dependent non-canonical inflammasome activation in a mouse model of enteropathogenic Citrobacter rodentium infection. Mechanistically, NOD2 and RIP2 regulate reactive oxygen species (ROS) production. Increased ROS in Rip2-deficient macrophages subsequently enhances c-Jun N-terminal kinase (JNK) signaling resulting in increased caspase-11 expression and activation, and more non-canonical NLRP3-dependant inflammasome activation. Intriguingly, this leads to protection of the colon epithelium for up to 10 days in Rip2-deficient mice infected with C. rodentium. Our findings designate NOD2 and RIP2 as key regulators of cellular ROS homeostasis and demonstrate for the first time that ROS regulates caspase-11 expression and non-canonical NLRP3 inflammasome activation through the JNK pathway

Women Education in Rural India

In India, the status of the girl child has been a subject of much discussion, contro­versy, and debate. From the start, girl children are seen as burdens rather than blessings, bearers of exorbitant dowries, who will eventually move into the homes of their husbands. There are some overwhelming cultural and economic reasons why female children are not receiving the same medical, emotional, and educational attention as their male counterparts. The result is a low literacy rate among women in rural areas. There has been an increasing proportion of women, who are literate in just 20 years. Despite the improvements, there continues to be a large gap between the educational levels of men and women in rural India. The present study is focused on status, causes, and recommendations for rural women education

Introduction About Child Health Status in India

Child health is a multifaceted problem which is directly linked to a large extent to mother’s health conditions, safe delivery conditions, socio-economic conditions of the family and the health care system. Over the time, the nation has implemented a number of child-centric programs, the poor health status of women and children in terms of high mortality and morbidity was another health priority in this country. Health facilities like hospitals and health centers were established for providing Maternal and Child Healthcare through antenatal, intra-natal and postnatal services. In addition, a number of special programs and schemes like immunization against vaccine-preventable diseases, nutrition interventions like iron and folic acid distribution and vitamin A supplementation, diarrheal disease control through Oral Rehydration Therapy (ORT), Acute Respiratory Infection (ARI) control program etc. were implemented over the past. In order to, ensure maximum benefit from these programs and to provide services in an integrated manner to these vulnerable groups strong monitoring system required

Effect of Nuclear Family in Participation of Activities

In nuclear families parents pay more attention to child education; they plan school, college, career after discussion with field experts. Such consciousness increases their intention towards quality education. Parents belonging to nuclear family pay more money rather than a conventional family. Parents have become more concerned for child In other families attention on a child is distributed and unable to concentrate child only. This social trend influence child performance and quality education. They have a financial plan also regarding the study

Role of the Nlrp3 Inflammasome in Microbial Infection

The intracellular Nod-like receptor Nlrp3 has emerged as the most versatile innate immune receptor because of its broad specificity in mediating immune response to a wide range of microbial or danger signals. Nlrp3 mediates assembly of the inflammasome complex in the presence of microbial components leading to the activation of caspase-1 and the processing and release of the pro-inflammatory cytokines IL-1β and IL-18. In this review, we give an update on the recent literature examining the role of Nlrp3 inflammasome in response to fungal, bacterial, and viral infections

Effect of Bio-degradation and Non Degradable Substances in Environment

Non-Biodegradable substances produce the greenhouse gasses, methane and carbon dioxide. Growing plants and trees on top of a landfill, a process known as ‘Phyto capping\u27, could reduce the production and release of these gasses. In certain parts of the world, it remains the most economical and simplest method of waste disposal. Biodegradation of organic matter in a landfill site occurs most rapidly when water comes into contact with the buried waste. An important step in the drive is to remove environmentally harmful materials from waste streams and drinking water. A synthetic clay known as swelling mica has the ability to separate ions of radium, a radioactive metal, from the water. The finding could have implications for radioactive and hazardous waste disposal, particularly in the cleanup of mill tailings left over from the processing of uranium for the nation\u27s nuclear industry. The tailings contain radium and heavy metals

Signal distortion from microelectrodes in clinical EEG acquisition systems

Many centers are now using high-density microelectrodes during traditional intracranial electroencephalography (iEEG) both for research and clinical purposes. These microelectrodes are FDA-approved and integrate into clinical EEG acquisition systems. However, the electrical characteristics of these electrodes are poorly described and clinical systems were not designed to use them; thus, it is possible that this shift into clinical practice could have unintended consequences. In this study, we characterized the impedance of over 100 commercial macro- and microelectrodes using electrochemical impedance spectroscopy (EIS) to determine how electrode properties could affect signal acquisition and interpretation. The EIS data were combined with the published specifications of several commercial EEG systems to design digital filters that mimic the behavior of the electrodes and amplifiers. These filters were used to analyze simulated brain signals that contain a mixture of characteristic features commonly observed in iEEG. Each output was then processed with several common quantitative EEG measurements. Our results show that traditional macroelectrodes had low impedances and produced negligible distortion of the original signal. Brain tissue and electrical wiring also had negligible filtering effects. However, microelectrode impedances were much higher and more variable than the macroelectrodes. When connected to clinical amplifiers, higher impedance electrodes produced considerable distortion of the signal at low frequencies (<60 Hz), which caused significant changes in amplitude, phase, variance and spectral band power. In contrast, there were only minimal changes to the signal content for frequencies above 100 Hz. In order to minimize distortion with microelectrodes, we determined that an acquisition system should have an input impedance of at least 1 GΩ, which is much higher than most clinical systems. These results show that it is critical to account for variations in impedance when analyzing EEG from different-sized electrodes. Data from microelectrodes may yield misleading results unless recorded with high-impedance amplifiers.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98632/1/1741-2552_9_5_056007.pd

Introduction to Satellite Education on Quality Management

Education provides access to subject matter experts, interaction with career role models. It provides interaction with students in other schools, increases access to information instructional resources, offers opportunities for staff development/in-service training, and increase school community linkages. The rapid growth of satellite networks has generated interest by many state officials in statewide satellite networks. Rural areas are showing great interest in interactive satellite instruction as a way to resolve teacher shortages and meet rigorous graduation requirements. Televised classes permitting live teacher-student interaction via satellite communication systems, and regular telephone lines provide equity increasing quality of educational opportunity

Importance of Primary Health Care in the Society

Primary health care (PHC) is the frontline care of the health care system that is comprehensive and coordinated. PHC provides multidisciplinary, patient-centered care with a focus on both the treatment and prevention of various conditions. It is the first point of contact to keep people well and improve their quality of life. A strong, accessible PHC system reduces pressure on hospitals by supporting people to manage their health issues in the society. The ultimate goal of primary health care is better health for all. WHO has identified key elements to achieving that goal: reducing exclusion and social disparities in health, organizing health services around people\u27s needs and expectations. The present paper is related to status and role of primary health care in India